Ηθοποιοί

• Johnny Depp — Captain Jack Sparrow
• Penélope Cruz — Angelica Teach
• Ian McShane — Captain Edward
• Sam Claflin — Philip Swift
• Richard Griffiths — King George II
• Kevin McNally — Joshamee Gibbs
• Geoffrey Rush — Captain Hector Barbossa
• Astrid Bergès-Frisbey — Syrena
• Christopher Fairbank — Ezekiel
• Bronson Webb — Cook
• Derek Mears — Master-at-Arms
• Anton Lesser — John Carteret
• Stephen Graham — Scrum
• Keith Richards — Captain Teague Sparrow
• Judi Dench — High Society Lady
• Luke Roberts — Captain of the Guard
• Greg Ellis — Lieutenant Theodore Groves
• Ian Mercer — Quartermaster
• Robbie Kay — Cabin Boy
• Steve Evets — Purser
• DeObia Oparei — Gunner
• Sebastian Armesto — King Ferdinand of the Spanish Empire
• Paul Bazely — Salaman
• Richard Thomson — Derrick
• Emilia Jones — English Girl
• Daniel Ings — Guard
• Damian O'Hare — Lieutenant Gillette
• Yuki Matsuzaki — Garheng
• Roger Allam — Prime Minister Henry Pelham
• Óscar Jaenada — The Spaniard
• Gemma Ward — Tamara - First Mermaid