Ηθοποιοί

• Noomi Rapace — Dr. Elizabeth Shaw
• Michael Fassbender — David
• Charlize Theron — Meredith Vickers
• Idris Elba — Janek
• Guy Pearce — Peter Weyland
• Logan Marshall-Green — Charlie Holloway
• Sean Harris — Fifield
• Rafe Spall — Millburn
• Emun Elliott — Chance
• Benedict Wong — Ravel
• Kate Dickie — Ford
• Patrick Wilson — Shaw's Father
• Ian Whyte — Last Engineer
• Robin Atkin Downes — Ship Computer Voice (voice)
• Lucy Hutchinson — Young Shaw
• Daniel James — Sacrifice Engineer