Näitlejad

• Taraji P. Henson — Katherine G. Johnson
• Kevin Costner — Al Harrison
• Octavia Spencer — Dorothy Vaughn
• Glen Powell — John Glenn
• Kirsten Dunst — Vivian Mitchell
• Mahershala Ali — Colonel Jim Johnson
• Aldis Hodge — Levi Jackson
• Alkoya Brunson — Kenneth Vaughn
• Amy Tipton — Woman Crying
• Andre Pushkin — Russian Scientist
• Bob Jennings — Navy Officer
• Corey Mendell Parker — Howard Vaughan (as Corey Parker)
• Cullen Moss — Mission Control Commander
• Dane Davenport — Alan Shepard
• David Kallaway — NASA Security Guard
• Donna Biscoe — Mrs. Joylette Coleman
• Evan Holtzman — Deke Slayton
• Gary Weeks — Reporter at Press Conference
• Howie Johnson — Library Security Guard
• Jaiden Kaine — Joshua Coleman
• Joe Knezevich — Wind Tunnel PA Announcer
• John Atwood — Newscaster
• Ken Strunk — Jim Webb
• Kimberly Quinn — Ruth
• Kurt Krause — Sam Turner
• Lidya Jewett — Young Katherine Coleman
• Maria Howell — Ms. Sumner
• Olek Krupa — Karl Zielinski
• Paul Ryden — TV Reporter at Cape Canaveral
• Rhoda Griffis — White Librarian
• Robert McKay — Pastor Ayres
• Ron Clinton Smith — White Cop
• Saniyya Sidney — Constance Johnson
• Afemo Omilami — Man Outside Store
• Frank Hoyt Taylor — Judge
• Jim Parsons — Paul Stafford
• Scott Michael Morgan — Bill Calhoun
• Wilbur Fitzgerald — Senator Patrick (as Wilbur T. Fitzgerald)
• Arnell Powell — Professor Graves
• Gregory Alan Williams — Marion Smithson (as G. Williams)
• Tequilla Whitfield — Eleanor
• Travis Smith — Scott Carpenter
• Randall Newsome — Russian Scientist
• Janelle Monáe — Mary Jackson