Näitlejad

• Shia LaBeouf — Sam Witwicky
• Megan Fox — Mikaela Banes
• Josh Duhamel — Captain Lennox
• John Turturro — Agent Simmons
• Peter Cullen — Optimus Prime (voice)
• Mark Ryan — Bumblebee (voice)
• Hugo Weaving — Megatron (voice)
• Charles Adler — Starscream (voice)
• Robert Foxworth — Ratchet (voice)
• Jess Harnell — Barricade (voice)
• Darius McCrary — Jazz (voice)
• Reno Wilson — Frenzy (voice)
• Jess Harnell — Barricade (voice)
• Tyrese Gibson — USAF Master Sgt. Epps
• Rachael Taylor — Maggie Madsen
• Anthony Anderson — Glen Whitman
• Jon Voight — John Keller
• Kevin Dunn — Ron Witwicky
• Julie White — Judy Witwicky
• Michael O'Neill — Tom Banacheck
• Amaury Nolasco — ACWO Jorge "Fig" Figueroa
• Zack Ward — First Sergeant Donnelly
• Jimmie Wood — Bonecrusher
• Bernie Mac — Bobby Bolivia
• Peter Jacobson — Mr. Hosney
• Samantha Smith — Sarah Lennox
• John Robinson — Miles
• Travis Van Winkle — Trent DeMarco
• Glenn Morshower — Colonel Sharp
• Frederic Doss — SOCCENT Op-Centre Tech
• Chris Ellis — Admiral Brigham
• Scott Peat — Pentagon Watch Commander
• Brian Stepanek — Sector Seven Agent
• Rick Gomez — Sheriff
• Tom Lenk — Analyst
• Colton Haynes — Cafe Kid
• Michelle Pierce — Socialite
• Odette Annable — Socialite
• Mike Fisher — Football Coach