Näyttelijät

• Natalie Portman
• Ashton Kutcher — Adam Franklin
• Kevin Kline — Alvin Franklin
• Cary Elwes — Dr. Stephen Metzner
• Greta Gerwig — Patrice
• Lake Bell — Lucy
• Olivia Thirlby — Katie Kurtzman
• Ludacris — Wallace
• Jake Johnson — Eli
• Mindy Kaling — Shira
• Talia Balsam — Sandra Kurtzman
• Ophelia Lovibond — Vanessa
• Guy Branum — Guy
• Ben Lawson — Sam
• Jennifer Irwin — Megan
• Adhir Kalyan — Kevin
• Abby Elliott — Joy
• Vedette Lim — Lisa
• Matthew Moy — Chuck
• Nealla Gordon — Lydia
• Mollee Gray — Sari
• Tyne Stecklein — Victoria
• Stefanie Scott — Young Emma Kurtzman
• Tim Matheson — Eli's Dad #2
• Nasim Pedrad — Writer
• Elizabeth Meriwether — Writer
• Seth Morris — Man with Dog