Näyttelijät

• Freddie Prinze Jr. — Fred
• Sarah Michelle Gellar — Daphne
• Matthew Lillard — Shaggy
• Linda Cardellini — Velma
• Seth Green — Patrick
• Tim Blake Nelson — Jacobo
• Alicia Silverstone — Heather
• Neil Fanning — Scooby-Doo (voice)
• Pat O'Brien — Himself
• Peter New — Daphne's Tattooed Fan #2
• Calum Worthy — Kid on Bike #2
• Colin Foo — Investor
• Peter Boyle — Old Man Wickles