Näyttelijät

• Frankie Muniz — Malcolm
• Erik Per Sullivan — Dewey
• Justin Berfield — Reese
• Jane Kaczmarek — Lois
• Bryan Cranston — Hal
• Christopher Masterson — Francis
• Craig Lamar Traylor — Stevie Kenarban
• David Anthony Higgins — Craig Feldspar
• James and Lukas Rodriguez — Jamie
• Emy Coligado — Piama Tananahaakna
• Kenneth Mars — Otto Mannkusser
• Catherine Lloyd Burns — Caroline Miller
• Daniel Von Bargen — Commandant Edwin Spangler
• Cloris Leachman — Ida
• Eric Nenninger — Eric Hansen
• Karim Prince — Stanley Winn
• Brenda Wehle — Lavernia
• Evan Matthew Cohen — Lloyd
• Kyle Sullivan — Dabney Hooper
• Gary Anthony Williams — Abraham 'Abe' Kenarban
• Will Jennings — Kyle
• Meagen Fay — Gretchen Mannkusser
• Hayden Panettiere — Jessica
• Tania Raymonde — Cynthia Sanders
• Merrin Dungey — Kitty Kenarban
• Sandy Ward — Pete
• Chris Eigeman — Lionel Herkabe
• Arjay Smith — Ken Finley
• Cameron Monaghan — Chad
• Danny McCarthy — Hanson
• Reagan Dale Neis — Nikki
• Brittany Finamore — Alison
• Julie Hagerty — Polly
• Amy Bruckner — Zoe
• Beth Grant — Dorene Hooper
• Bea Arthur — Madame White
• Christopher Lloyd — Walter
• Laurie Metcalf — Susan
• Jennette McCurdy — Daisy
• Lisa Foiles — Mallory
• Mimi Paley — Renee