Näyttelijät

• Amanda Abbington — Mary Morstan
• Benedict Cumberbatch — Sherlock Holmes
• Louise Brealey — Molly Hooper
• Mark Gatiss — Mycroft Holmes
• Martin Freeman — John Watson
• Rupert Graves — Greg Lestrade
• Una Stubbs — Mrs. Hudson
• Andrew Scott — Jim Moriarty
• Lara Pulver — Irene Adler
• Lars Mikkelsen — Charles Augustus Magnussen
• Sian Brooke — Elizabeth
• Toby Jones — Culverton Smith