Rollebesetning

• Tom Cruise — Jerry Maguire
• Cuba Gooding Jr. — Rod Tidwell
• Renée Zellweger — Dorothy Boyd
• Kelly Preston — Avery Bishop
• Jay Mohr — Bob Sugar
• Jerry O'Connell — Frank Cushman
• Bonnie Hunt — Laurel Boyd
• Regina King — Marcee Tidwell
• Todd Louiso — Chad the Nanny
• Donal Logue — Rick
• Angela Goethals — Kathy Sanders
• Eric Stoltz — Ethan Valhere
• Lucy Liu — Former girlfriend
• Ivana Milicevic — Former Girlfriend
• Emily Procter — Former Girlfriend
• Beau Bridges — Matt Cushman
• Mark Pellington — Bill Dooler
• Jeremy Suarez — Tyson Tidwell
• Drake Bell — Jesse Remo
• Rick Johnson — John Swenson
• Toby Huss — Steve Remo
• Lamont Johnson — Weepy Athlete
• Katarina Witt — Katarina Witt
• Jann Wenner — Scully
• Ingrid Beer — Anne-Louise
• Glenn Frey — Dennis Wilburn
• Christine Cavanaugh — Mrs. Remo
• Aries Spears — Tee Pee
• Alison Armitage — Former Girlfriend
• Jonathan Lipnicki — Ray Boyd