Rollebesetning

• Charlie Hunnam — Raleigh Becket
• Rinko Kikuchi — Mako Mori
• Idris Elba — Stacker Pentecost
• Charlie Day — Dr. Newton Geiszler
• Burn Gorman — Dr. Hermann Gottlieb
• Max Martini — Herc Hansen
• Robert Kazinsky — Chuck Hansen
• Robert Maillet — Lt. Aleksis Kaidanovsky
• Heather Doerksen — Lt. Sasha Kaidanovsky
• Larry Joe Campbell — Tommy T
• Diego Klattenhoff — Yancy Becket
• Santiago Segura — Wizened Man
• Joe Pingue — Captain Merrit
• Milton Barnes — McTighe
• Ron Perlman — Hannibal Chau
• Clifton Collins Jr. — Tendo Choi
• Brad William Henke — Miles
• Jane Watson — Raleigh and Yancy's Mom
• Jung-Yul Kim — Hannibal Chau Thug
• Mana Ashida — Young Mako
• Brian Frank — 1st Officer
• Ellen McLain — Gipsy Danger AI (voice)
• Robin Thomas — American UN Representative
• Julian Barnes — British UN Representative
• Sebastian Pigott — Engineer
• J.C. Kenny — TV Reporter
• Robert Morse — Raleigh and Yancy's Dad
• Duncan McLeod — Saltchuck Crew
• Louis Paquette — Saltchuck Crew
• Frank Nakashima — UN Representative
• Terry Belleville — UN Representative
• Farzad Sadrian — UN Representative
• Mishu Vellani — UN Representative
• Clive Walton — UN Representative
• Peter Kosaka — Young Mako's Father
• Joshua Peace — Officer
• David Fox — Old Man on Beach
• David Richmond-Peck — Canadian UN Representative
• Mike Chute — Saltchuck Crew
• Victoria Sawal — Chinese Girl in Anti-Kaiju Refuge