Rollebesetning

• Kurt Angle — FDNY Fire Chief
• Ian Ziering — Fin Shepard
• Vivica A. Fox — Skye
• Kari Wuhrer — Ellen Brody
• Mark McGrath — Martin Brody
• Judd Hirsch — Ben
• Tiffany Shepis — Chrissie
• Andy Dick — Officer Doyle
• Billy Ray Cyrus — Doctor Quint
• Perez Hilton — Impatient Passenger
• Robert Klein — The Mayor
• Kelly Ripa — Herself
• Wil Wheaton — Passenger
• Tara Reid — April Wexler
• Kelly Osbourne — Flight Attendant
• Judah Friedlander — Brian
• Richard Kind — Harland 'The Blaster' McGuinness
• Robert Hays — Captain Bob Wilson
• Biz Markie — Vinnie
• Jared Fogle — Jared from Subway
• Downtown Julie Brown — Nurse Fletcher
• Michael Strahan — Himself
• Matt Lauer — Himself
• Al Roker — Himself
• Kelly Oxford — Annoyed Woman on Plane