Rollebesetning

• Brandon Routh — Superman / Clark Kent
• Kate Bosworth — Lois Lane
• Kevin Spacey — Lex Luthor
• James Marsden — Richard White
• Parker Posey — Kitty Kowalski
• Frank Langella — Perry White
• Kal Penn — Stanford
• Marlon Brando — Jor-El
• Peta Wilson — Bobbie-Fae
• Alison Araya — Actor
• Tristan Lake Leabu — Jason White
• Sam Huntington — Jimmy Olsen
• Rob Flanagan — Bank Gunner
• David Fabrizio — Brutus
• Noel Neill — Gertrude Vanderworth
• Keegan Joyce — Boy with Camera
• Jack Larson — Bo the Bartender
• Ian Roberts — Riley
• Eva Marie Saint — Martha Kent