Rollebesetning

• Anthony Edwards — Mark Greene
• George Clooney — Doug Ross
• Sherry Stringfield — Susan Lewis
• Noah Wyle — John Carter
• Julianna Margulies — Carol Hathaway
• Eriq La Salle — Peter Benton
• Gloria Reuben — Jeanie Boulet
• Laura Innes — Kerry Weaver
• Maria Bello — Anna Del Amico
• Alex Kingston — Elizabeth Corday
• Kellie Martin — Lucy Knight
• Paul McCrane — Robert Romano
• Goran Visnjic — Luka Kovac
• Michael Michele — Cleo Finch
• Erik Palladino — Dave Malucci
• Ming-Na Wen — Jing-Mei Chen
• Maura Tierney — Abby Lockhart
• Sharif Atkins — Michael Gallant
• Mekhi Phifer — Greg Pratt
• Parminder Nagra — Neela Rasgotra
• Linda Cardellini — Samantha Taggart
• Shane West — Ray Barnett
• Scott Grimes — Archie Morris
• John Stamos — Tony Gates
• David Lyons — Simon Brenner
• Angela Bassett — Catherine Banfield
• William H. Macy — David Morgenstern
• Abraham Benrubi — Jerry Markovic
• Conni Marie Brazelton — Connie Oligario
• Ellen Crawford — Lydia Wright
• Deezer D — Malik McGrath
• Yvette Freeman — Haleh Adams
• Vanessa Marquez — Wendy Goldman
• Lily Mariye — Lily Jarvik
• CCH Pounder — Angela Hicks
• Amy Aquino — Janet Coburn
• Laura Cerón — Chuny Marquez
• John Aylward — Donald Anspaugh
• Jorja Fox — Maggie Doyle
• Troy Evans — Frank Martin
• Leland Orser — Lucien Dubenko
• Sara Gilbert — Jane Figler
• John Leguizamo — Victor Clemente
• Gil McKinney — Paul Grady
• Stanley Tucci — Kevin Moretti
• Malgorzata Gebel — Bogdana "Bob" Livetsky Romansky