Rollebesetning

• Matthew Fox — Jack Shephard
• Evangeline Lilly — Kate Austen
• Terry O'Quinn — John Locke
• Naveen Andrews — Sayid Jarrah
• Josh Holloway — James "Sawyer" Ford
• Jorge Garcia — Hugo "Hurley" Reyes
• Daniel Dae Kim — Jin-Soo Kwon
• Kim Yun-jin — Sun Kwon
• Michael Emerson — Benjamin Linus
• Elizabeth Mitchell — Juliet Burke
• Henry Ian Cusick — Desmond Hume
• Maggie Grace — Shannon Rutherford
• Malcolm David Kelley — Walt Lloyd
• Ian Somerhalder — Boone Carlyle
• Harold Perrineau — Michael Dawson
• Emilie de Ravin — Claire Littleton
• Dominic Monaghan — Charlie Pace
• Michelle Rodriguez — Ana-Lucia Cortez
• Adewale Akinnuoye-Agbaje — Mr. Eko
• Cynthia Watros — Elizabeth "Libby" Smith
• Rodrigo Santoro — Paulo
• Kiele Sanchez — Nikki Fernandez
• Jeremy Davies — Daniel Faraday
• Ken Leung — Miles Straume
• Rebecca Mader — Charlotte Lewis
• Sonya Walger — Penny Widmore
• Mira Furlan — Danielle Rousseau
• Tania Raymonde — Alexandra Rousseau
• Jeff Fahey — Frank Lapidus
• Kevin Durand — Martin Keamy
• Nestor Carbonell — Richard Alpert
• L. Scott Caldwell — Rose Nadler
• Zuleikha Robinson — Ilana Verdansky
• M.C. Gainey — Tom
• Sam Anderson — Bernard Nadler
• John Terry — Christian Shephard