Aktorët

• Millie Bobby Brown — Enola Holmes
• Henry Cavill — Sherlock Holmes
• Sam Claflin — Mycroft Holmes
• Helena Bonham Carter — Mrs. Holmes
• Louis Partridge — Viscount Tewkesbury
• Burn Gorman — Linthorn
• Adeel Akhtar — Lestrade
• Susan Wokoma — Edith
• Hattie Morahan — Caroline Tewkesbury
• David Bamber — Whimbrel Tewkesbury
• Frances De La Tour — The Dowager
• Claire Rushbrook — Lane
• Fiona Shaw — Miss Harrison