Aktorët

• Kate Beckinsale — Selene
• Michael Ealy — Detective Sebastian
• Stephen Rea — Dr. Jacob Lane
• Sandrine Holt — Lida
• Theo James — David
• Charles Dance — Thomas
• Wes Bentley — Antigen Scientist
• India Eisley — Eve
• Sanny van Heteren — British newscaster
• Jacob Blair — Kolb (Officer)
• Robert Lawrenson — Waterfront Cop
• Dan Payne — Lycan 2
• Mark Gibbon — Announcing Guard
• Tyler McClendon — Scientist
• Panou — Old City Cop #1
• Ian Rozylo — Old City Cop #2
• Kris Holden-Ried — Quint Lane
• John Innes — Medical Supervisor
• Lee Majdoub — Desk Guard
• Adam Greydon Reid — Med Tech
• Benita Ha — Surgical Nurse
• Kurt Max Runte — Leader of the Troop
• Catlin Adams — Olivia
• Christian Tessier — Security Guard #1