Oyuncular

• Anna Madeley — Mary Melrose
• Benedict Cumberbatch — Patrick Melrose
• Blythe Danner — Nancy
• Celia Imrie — Kettle
• Holliday Grainger — Bridget Watson Scott
• Hugo Weaving — David Melrose
• Indira Varma — Anne Moore
• Jennifer Jason Leigh — Eleanor Melrose
• Jessica Raine — Julia
• Pip Torrens — Nicholas Pratt
• Prasanna Puwanarajah — Johnny Hall
• Sebastian Maltz — Young Patrick Melrose
• Allison Williams — Marianne Banks