الممثلون

• Reese Witherspoon — Susan Murphy
• Hugh Laurie — Dr. Cockroach Ph.D. (voice)
• Seth Rogen — B.O.B. (voice)
• Will Arnett — The Missing Link (voice)
• Kiefer Sutherland — General W.R. Monger (voice)
• Rainn Wilson — Gallaxhar (voice)
• Paul Rudd — Derek Dietl (voice)
• Stephen Colbert — President Hathaway (voice)
• Jimmy Kimmel — Insectosaurus (voice)
• Amy Poehler — Computer (voice)
• Julie White — Wendy Murphy (voice)
• Jeffrey Tambor — Carl Murphy (voice)
• Rich Dietl — Commander / Advisor Smith (voice)
• Tom McGrath — Wilson (voice)
• Mike Mitchell — Advisor Wedgie (voice)
• Kent Osborne — Technician Jerry (voice)
• Latifa Ouaou — Advisor Ouaou / Mrs. Ronson / Female Advisor #2 / Panicked Guest (voice)
• David P. Smith — Soldier #1 / Advisor Jackson (voice)
• Lisa Stewart — Bridesmaid Candy (voice)
• John Krasinski — Cuthbert (voice)
• Stephen Kearin — Technician Bee (voice)
• Rosemary Alexander — ADR Group (voice)
• Jack Blessing — ADR Group (voice)
• Nicholas Guest — ADR Group (voice)
• Bridget Hoffman — ADR Group (voice)
• Edie Mirman — ADR Group (voice)
• Chris Miller — Advisor Cole / Army Commander Jones (voice)
• Paul Pape — ADR Group (voice)
• Marcelo Tubert — ADR Group (voice)
• Ed Helms — News Reporter (voice)
• Renée Zellweger — Katie (voice)
• Sean Bishop — Private Bullhorn / Helicopter Pilot / Advisor Ortega (voice)
• Rob Letterman — Secret Service Man #1 / Lieutenant (voice)
• Conrad Vernon — Advisor Hawk / Advisor Dither / Minister / Secret Service Man #2 / Mama Dietl (voice)
• Richard Steven Horvitz — ADR Group (voice)
• Hope Levy — ADR Group (voice)
• Michelle Ruff — ADR Group (voice)