Reparto

• Jim Carrey — Grinch
• Taylor Momsen — Cindy Lou Who
• Bill Irwin — Lou Lou Who
• Molly Shannon — Betty Lou Who
• Christine Baranski — Martha May Whovier
• Jeffrey Tambor — Mayor Augustus Maywho
• Jeremy Howard — Drew Lou Who
• T.J. Thyne — Stu Lou Who
• Lacey Kohl — Christina Whoterberry
• Clint Howard — Whobris
• Josh Ryan Evans — 8-Year-Old Grinch
• Mindy Sterling — Clarnella
• Rachel Winfree — Rose
• Rance Howard — Elderly Timekeeper
• Suzanne Krull — Shopper
• Anthony Hopkins — Narrator (voice)