Reparto

• Robert De Niro — Stan Harris
• Halle Berry — Nurse Aimee
• Cary Elwes — Stan's Doctor
• Alyssa Milano — Nurse Mindy
• Common — Soldier
• Jessica Biel — Tess Byrne
• Sarah Paulson — Grace Schwab
• Carla Gugino — Spiritual Dr. Morriset
• Katherine Heigl — Laura Carrington
• Jon Bon Jovi — Daniel Jensen
• Sofía Vergara — Ava
• Ashton Kutcher — Randy
• Lea Michele — Elise
• Jim Belushi — Building Super
• Sarah Jessica Parker — Kim Doyle
• Abigail Breslin — Hailey Doyle
• Josh Duhamel — Sam
• Jack McGee — Grandpa Jed
• Cherry Jones — Mrs. Rose Ahern
• Hilary Swank — Claire Morgan
• Ludacris — Brendan
• David Valcin — Reporter Murphy
• Héctor Elizondo — Kominsky
• Nat Wolff — Walter
• Michelle Pfeiffer — Ingrid Withers
• Zac Efron — Paul
• Yeardley Smith — Maude
• Ryan Seacrest — Himself
• Seth Meyers — Griffin Byrne
• Katherine McNamara — Lily Bowman
• Jake T. Austin — Seth
• Matthew Walker — Engineer Douglas
• Michael Bloomberg — Himself
• Fiona Choi — Balinese Woman - Resolution Tour
• Mara Davi — Mika
• Russell Peters — Chef Sunil
• Til Schweiger — James Schwab
• Matthew Broderick — Mr. Buellerton
• John Lithgow — Jonathan Cox