Reparto

• Antonio Banderas — Puss in Boots
• Salma Hayek — Kitty Softpaws (voice)
• Constance Marie — Imelda (voice)
• Mike Mitchell — Andy Beanstalk (voice)
• Rich Dietl — Bounty Hunter (voice)
• Ryan Crego — Luis (voice)
• Bob Joles — Giuseppe (voice)
• Nina Barry — Ivana / Charo (voice)
• Zach Galifianakis — Humpty Dumpty (voice)
• Billy Bob Thornton — Jack (voice)
• Amy Sedaris — Jill (voice)
• Guillermo del Toro — Comandante / Hombre del bigote (voice)
• Conrad Vernon — Raoul / Soldier (voice)
• Bob Persichetti — Ohhh Cat