Reparto

• Freddie Prinze Jr. — Fred Jones
• Sarah Michelle Gellar — Daphne Blake
• Matthew Lillard — Shaggy
• Linda Cardellini — Velma Dinkley
• Rowan Atkinson — Emile Mondavarious
• Isla Fisher — Mary Jane
• Miguel A Núñez, Jr — Voodoo Maestro
• Steven Grives — N' Goo Tuana
• Neil Fanning — Scooby-Doo
• Scott Innes — Scrappy-Doo
• Pamela Anderson — Herself
• Kristian Schmid — Brad
• Sam Greco — Zarkos
• Michala Banas — Carol
• Mark McGrath — Sugar Ray