Cast

• J.B. Smoove — Larry (segment "The Proposition")
• Kristen Bell — Fake Supergirl (segment "Super Hero Speed Dating")
• Julie Ann Emery — Clare (segment "Homeschooled")
• Seann William Scott — Pete (segment "Happy Birthday")
• Emma Stone — Veronica (segment "Veronica")
• Kate Winslet — Beth (segment "The Catch")
• Hugh Jackman — Davis (segment "The Catch")
• Chris Pratt — Jason (segment "The Proposition")
• Gerard Butler — Leprechaun 1 & 2 (segment "Happy Birthday")
• Elizabeth Banks
• Seth MacFarlane — Seth MacFarlane (segment
• Dennis Quaid — Charlie Wessler (segment "The Pitch")
• Greg Kinnear — Griffin Schraeder (segment "The Pitch")
• Aasif Mandvi — Robert (segment "iBabe")
• Justin Long — Fake Wonder Woman (segment "Super Hero Speed Dating")
• Leslie Bibb — Fake Wonder Woman (segment "Super Hero Speed Dating")
• Christopher Mintz-Plasse — Mikey (segment "Middleschool Date")
• Stephen Merchant — Donald (segment "Truth or Dare")
• Zen Gesner — Stripper (segment "Truth or Dare")
• Terrence Howard — Coach Jackson (segment "Victory's Glory")
• Eric Stuart — Narrator (segment "Victory's Glory")
• Michelle Gunn — Mommy (segment "Beezel")
• Anna Faris — Vanessa (segment "The Proposition")
• Halle Berry — Emily (segment "Truth or Dare")
• Richard Gere — Robert (segment "iBabe")
• Uma Thurman — Fake Lois Lane (segment "Super Hero Speed Dating")
• Naomi Watts — Samantha (segment "Homeschooled")
• Common — Bob Mone (segment "The Pitch")
• Charlie Saxton — Jay (segment "The Pitch")
• Will Sasso — Jerry (segment "The Pitch")
• Odessa Rae — Danita (segment "The Pitch")
• Julie Claire — Pamela (segment "The Catch")
• Katie Finneran — Angie (segment "The Catch")
• Roy Jenkins — Ray (segment "The Catch")
• Jeremy Allen White — Kevin (segment "Homeschooled")
• Liev Schreiber — Robert (segment "Homeschooled")
• Alex Cranmer — Sean (segment "Homeschooled")
• Jarrad Paul — Bill (segment "The Proposition")
• Aaron LaPlante — Friend (segment "The Proposition")
• Kieran Culkin — Neil (segment "Veronica")
• Arthur French — Old Man (segment "Veronica")
• Brooke Davis — Tall Lady (segment "Veronica")
• John Shuman — Short Guy (segment "Veronica")
• Kate Bosworth — Arlene (segment "iBabe")
• Jack McBrayer — Brian (segment "iBabe")
• Jason Sudeikis — Fake Batman (segment "Super Hero Speed Dating")
• Bobby Cannavale — Fake Superman (segment "Super Hero Speed Dating")
• John Hodgman — Fake Penguin (segment "Super Hero Speed Dating")
• Katrina Bowden — Woman (segment "Super Hero Speed Dating")
• Phil Crowley — Narrator (segment "Machine Kids")
• Rightor Doyle — Photocopier Man 1 (segment "Machine Kids")
• Chloë Grace Moretz — Amanda (segment "Middleschool Date")
• Patrick Warburton — Dad (segment "Middleschool Date")
• Jimmy Bennett — Nathan (segment "Middleschool Date")
• Matt Walsh — Amanda's Dad (segment "Middleschool Date")
• Johnny Knoxville — Pete (segment "Happy Birthday")
• Sayed Badreya — Large Man (segment "Truth or Dare")
• Nicole Polizzi — Snooki (segment "Truth or Dare") (as Nicole Elizabeth Polizzi)
• Ricki Lander — Nurse Elizabeth (segment "Truth or Dare")
• Ben Harris — Blanco the Bartender (segment "Truth or Dare")
• Aaron Jennings — Anthony (segment "Victory's Glory")
• Jay Ellis — Lucious (segment "Victory's Glory")
• Brett Davern — White Guy 2 (segment "Victory's Glory")
• Sean Rosales — White Guy 4 (segment "Victory's Glory")
• Logan Holladay — White Guy 5 (segment "Victory's Glory")
• Josh Duhamel — Anson (segment "Beezel")
• Emily Alyn Lind — Birthday Girl (segment "Beezel")
• Julie McNiven — ATM Woman (segment "Machine Kids")