Cast

• Anna Faris — Cindy Campbell
• Regina Hall — Brenda Meeks
• Kevin Hart — CJ
• Simon Rex — George
• Anthony Anderson — Mahalik
• Charlie Sheen — Tom
• Leslie Nielsen — President Baxter Harris
• Camryn Manheim — Trooper Champlin
• George Carlin — The Architect
• Jenny McCarthy-Wahlberg — Kate
• Pamela Anderson — Becca
• Jeremy Piven — Ross Giggins
• Ajay Naidu — Sayaman
• Denise Richards — Annie
• Queen Latifah — Aunt Shaneequa/The Oracle
• Eddie Griffin — Orpheus
• Macy Gray — Herself
• Simon Cowell — Himself
• Timothy Stack — Carson Ward
• D.L. Hughley — John Wilson
• Elaine Klimaszewski — Elaine
• Diane Klimaszewski — Diane
• Raekwon — Himself
• Marny Eng — Tabitha
• Jianna Ballard — Sue
• Darrell Hammond — Father Muldoon
• Dexter Bell — Toilet Guy
• Fat Joe — Himself
• Ja Rule — Agent Thompson
• Master P — Himself
• Redman — Himself
• Method Man — Himself
• RZA — Himself
• Drew Mikuska — Cody
• William S. Taylor — Mr. Meeks
• Patricia Idlette — Mrs. Meeks
• Lori Stewart — Tabitha's Mother
• Edward Moss — MJ
• Dee Jay Jackson — Zubie
• U-God — Himself
• Naomi Lawson-Baird — Sweet Tabitha
• Monica Dillon — Brenda's Grandmother