Cast

• Tom Holland — Peter Parker / Spider-Man
• Samuel L. Jackson — Nick Fury
• Jake Gyllenhaal — Quentin Beck / Mysterio
• Marisa Tomei — May Parker
• Jon Favreau — Happy Hogan
• Zendaya — MJ
• Jacob Batalon — Ned Leeds
• Tony Revolori — Flash Thompson
• Angourie Rice — Betty Brant
• Remy Hii — Brad Davis
• Martin Starr — Mr. Harrington
• J.B. Smoove — Mr. Dell
• Cobie Smulders — Maria Hill
• Numan Acar — Dimitri
• Jorge Lendeborg Jr. — Jason Ionello
• Zach Barack — Zach
• Zoha Rahman — Zoha
• Yasmin Mwanza — Yasmin
• Joshua Sinclair-Evans — Josh
• Tyler Luke Cunningham — Tyler
• Sebastián Capitán Viveros — Sebastian
• Toni Garrn — The Seamstress
• Peter Billingsley — William Ginter Riva
• Clare Dunne — Victoria
• Nicholas Gleaves — Guterman
• Claire Rushbrook — Janice
• J.K. Simmons — J. Jonah Jameson
• Dawn Michelle King — E.D.I.T.H.
• Jeroen van Koningsbrugge — Dutch Soccer Hooligan
• Michael de Roos — Dutch Soccer Hooligan
• Jan-Paul Buijs — Dutch Soccer Hooligan
• Sergio Pierattini — Venetian Glassblower
• Anjana Vasan — Queens Reporter
• Brian Law — Queens Reporter
• Evelyn Mok — Queens Reporter
• Tatiana Lunardon — Italian TV Newsreader
• Giada Benedetti — Italian Customs Officer
• Lukáš Bech — Helpful Dutch Man
• Alessandro Giuggioli — Italian Street Vendor
• Petr Opava — Opera Singer
• Giuseppe Andriolo — Caricaturist
• Pat Kiernan — Himself