Cast

• Margot Robbie — Harley Quinn
• Idris Elba — Bloodsport
• John Cena — Peacemaker
• Joel Kinnaman — Colonel Rick Flag
• Sylvester Stallone — King Shark
• Daniela Melchior — Ratcatcher 2
• David Dastmalchian — Polka-Dot Man
• Viola Davis — Amanda Waller
• Peter Capaldi — Thinker
• Michael Rooker — Brian Durlin/Savant
• Jai Courtney — Digger Harkness/Captain Boomerang
• Alice Braga — Sol Soria
• Jennifer Holland — Emilia Harcourt
• Steve Agee — John Economos
• Juan Diego Botto — Silvio Luna
• Storm Reid — Tyla DuBois
• Joaquín Cosío — General Mateo Suarez
• Pete Davidson — Richard Hertz / Blackguard
• Flula Borg — Javelin
• Nathan Fillion — T.D.K.
• Mayling Ng — Mongal
• Sean Gunn — Weasel
• Taika Waititi — Ratcatcher
• Tinashe Kajese — Flo Crawley
• Lynne Ashe — Polka-Dot Man's Mom
• Pom Klementieff — La Gatita Amable Dancer (uncredited)
• Stephen Blackehart — Briscoe
• Terence Rosemore — Crew Chief
• Diany Rodriguez — Star-Crossed Gal
• Andrea Andrade — La Gatita Waitress
• Rey Hernandez — Teniente
• Fernando Martinez — Sliced Dome Soldado
• Ray Benitez — Coronel
• Reinaldo Faberlle — Large Guerrilla
• Jonathan Ralph Fritschi — Delicious Hot Dog Guerrilla
• Josh Ventura — Astronaut
• Gerardo Davila — General Vera
• Julio Cesar Ruiz — Milton