演员

• David Duchovny — Dr. Ira Kane
• Julianne Moore — Dr. Allison Reed, CDC
• Orlando Jones — Prof. Harry Phineas Block
• Seann William Scott — Wayne Grey
• Ted Levine — General Russell Woodman
• Ethan Suplee — Deke
• Dan Aykroyd — Governor Lewis
• Katharine Towne — Nadine
• Gregory Itzin — Cartwright
• Sarah Silverman — Denise
• Wayne Duvall — Dr. Paulson
• John Cho — Student
• Lee Garlington — Reporter
• Michael McGrady — Fireman
• Andrew Bowen — Road Worker
• Stephanie Hodge — Jill Mason
• Michelle Wolff — Carla
• Kyle Gass — Officer Drake
• Jerry Trainor — Tommy
• Jennifer Savidge — Clare
• Wendy Braun — Nurse Tate
• Michael Chapman — Sheriff Long
• Michael Bower — Danny
• Mary Pat Gleason — Customer
• Chris Wylde — Student
• Ty Burrell — Colonel Flemming
• Steven Gilborn — Judge Guilder