Cast

• Alec Baldwin — Dr. Julian Bailes
• David Morse — Mike Webster
• Arliss Howard — Dr. Joseph Maroon
• Eddie Marsan — Dr. Steven DeKosky
• Hill Harper — Christopher Jones
• Adewale Akinnuoye-Agbaje — Dave Duerson
• Stephen Moyer — Dr. Ron Hamilton
• Elizabeth Tulloch — Keana Strzelczyk
• Jason Davis — Defense Attorney
• Joni Bovill — Mrs. Scott
• Dan Ziskie — Paul Tagliabue
• Alison Moir — Colleen Bailes
• Will Smith — Dr. Bennet Omalu
• Albert Brooks — Dr. Cyril Wecht
• Gugu Mbatha-Raw — Prema Mutiso
• Mike O'Malley — Daniel Sullivan
• Richard T. Jones — Andre Waters
• Paul Reiser — Dr. Elliot Pellman
• Luke Wilson — Roger Goodell
• Matthew Willig — Justin Strzelczyk
• Sara Lindsey — Gracie
• Kevin Jiggetts — FBI Agent
• Gary Grubbs — FBI Agent
• L. Scott Caldwell — Waters' Mother
• Joshua Reyes — Graveyard Tech
• Holt McCallany — Angry Neurologist
• Kelley Davis — Assistant
• Randy Kovitz — Deputy Mayor
• Mike Clark — TV Reporter (Interview)
• Phillip Chorba — Tech
• Dino Rende — Strzelczyk's Son
• Cindy Jackson — Paramedic
• Scott Miller — Contractor